Which supportive measure reduces risk of infection in thrombocytopenic patients?

• A. Platelet transfusions as indicated by thresholds; monitor for bleeding; minimize invasive procedures; implement bleeding precautions.
• B. Administer vitamin C routinely.
• C. Avoid all contact with others.
• D. Prophylactic broad-spectrum antibiotics for all patients.

Answer: (A)

Preventing bleeding is central to lowering infection risk in thrombocytopenic patients. When platelet counts are low, even minor mucosal bleeds can occur, and bleeding itself often leads to invasive procedures or medical interventions that raise infection risk. Transfusing platelets as needed to keep counts above the bleeding threshold helps maintain hemostasis, preserves mucosal integrity, and reduces the need for invasive monitoring or catheterization. Together with vigilant bleeding monitoring and strict bleeding precautions (gentle care, minimizing invasive procedures, and careful venipuncture), this approach lowers opportunities for infection.

Routine vitamin C, avoiding all contact, and universal prophylactic broad-spectrum antibiotics aren’t appropriate strategies here: vitamin C doesn’t address bleeding risk, complete avoidance of contact isn’t feasible, and broad-spectrum antibiotics for everyone aren’t indicated due to resistance and unnecessary exposure.