What is recommended when a patient develops infusion-related symptoms during a monoclonal antibody infusion?

• A. Stop the infusion and restart later
• B. Continue at the same rate
• C. Monitor vitals every 15–30 minutes, assess for symptoms, and notify clinician if reactions occur.
• D. Administer extra chemotherapy

Answer: (C)

When infusion-related symptoms occur with a monoclonal antibody, the priority is close monitoring and prompt escalation to the clinician. Checking vitals every 15–30 minutes, assessing the full range of symptoms, and notifying the clinician if any reaction appears allows for timely evaluation and appropriate intervention. This approach lets the clinician decide whether to slow or pause the infusion, provide supportive treatment, or adjust the plan, ensuring patient safety while responding to the reaction. Continuing at the same rate without assessment or delaying clinician input could miss a worsening reaction, so ongoing observation and timely communication are essential.