Clinical trials evaluating outcomes in cancer patients found improved overall survival when receiving an RDI at least what percentage?

• A. 75%
• B. 85%
• C. 90%
• D. 65%

Answer: (B)

Relative dose intensity shows how much chemotherapy is given over time compared with what was planned. Keeping a higher RDI means delivering the intended dose on schedule, which matters because maintaining dose density can improve tumor kill and survival. In many cancer trials, achieving an RDI of at least 85% is associated with better overall survival than lower RDIs. This threshold reflects a practical target where staying at or above this level preserves treatment effectiveness while still allowing for manageable toxicity with supportive care. Values below this, such as 75% or 65%, are less consistently linked to improved survival, while 90% isn’t the commonly cited minimum. So the best-supported minimum RDI linked to better survival is 85%.