According to NCCN Older Adult Oncology Guidelines (version 1.2015), more than 60% of cancers in the United States occur in people age ____ and older.

• A. 60
• B. 65
• C. 70
• D. 75

Answer: (B)

Cancer burden increases with age, so most cancers occur in older adults. In the NCCN Older Adult Oncology Guidelines, 65 and older is the threshold used to define that group. Data show that more than 60% of cancers are diagnosed in people aged 65 and up, reflecting the accumulation of risk factors and aging-related changes. Therefore, the statement points to 65 as the age when more than 60% of cancers occur. The other ages don’t align with that specific guideline threshold: 60 is younger than the standard older-adult cut-off, while 70 or 75 would imply a different framing, not the guideline’s stated threshold.